Research Interest: Business Economics, Knowledge Management, Cost Benefit Analysis Method – application in company and in medical device market development, Healthcare, efectivness of medical equipment development. 

Research Interest: Surgical planning and simulation in esthetical facial surgeryTelemedicine o Biomedical engineering 

Research Interest:  Biomedical  instrumentation,  Health  monitoring  system,  System  modeling  and control, robotics

Research Interest: Medical Image Analysis and Processing  Computer Simulations of Nanoscale Systems  Communications and Mobile Computing  Bioinformatics and Computational Biology Computational Neuroscience and Vascular Flow Dynamics Biometrics and Bio-robotics Computer Aided Diagnosis and Guided Surgerya

Weihua Qiao, MD, PhD, is a Cardiovascular Surgeon and Associate Professor of Surgery at Union Hospital, Tongji Medical College, Huazhong University of Science and Technology. Dr. Qiao earned his medical degree from Chongqing Medical University in 2011. He obtained his PhD in the Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology with Dr. Nianguo Dong in 2016. His clinical interests include complex congenital cardiac surgery, minimally invasive cardiac surgery, and cardiac transplantation. Dr. Qiao serves as Principal Investigator on grants funded by National Key Research and Development Plan of China, National Natural Science Foundation of China, and other national/funding resources. His research is focused on biomedical materials and cardiovascular tissue engineering. Dr. Qiao has published more than 40 peer-review research papers including Circulation, European Heart Journal, Advanced Functional Materials and Acta Biomaterialia, and filed more than 10 patents. He has served as an editorial member and peer reviewer for several scientific journals in cardiovascular research and biomaterials. He has also served as mentor or advisor for a number of postdoctoral fellows, medical students, graduate and undergraduate students.

Research Interest: Biomedical materials and cardiovascular tissue engineering.

Publication List:

1. Ziwen Cai^#, Miaomiao Zhu^#, Li Xu^#, Yue Wang, Yin Xu, Wai Yen Yim, Hong Cao, Ruikang Guo, Xiang Qiu, Ximiao He, Jiawei Shi, Weihua Qiao* and Nianguo Dong*. Directed Differentiation of Human Induced Pluripotent Stem Cells to Heart Valve Cells. Circulation. 2024. DOI: 10.1161/CIRCULATIONAHA.123.065143. (Co-corresponding author).
2. Shijie Wang, Weihua Qiao*, Nianguo Dong*. Residual shunt and microthrombosis associated with new-onset migraine after transcatheter atrial septal defect closure. European Heart Journal. 2023, 44(43): 4605-4605. (Co-corresponding author).
3. Ying Zhou^#, Ge Yan^#, Shuyu Wen, Wai Yen Yim, Zihao Wang, Xing Chen, Yin Xu, Xue Chen, Hong Cao, Peng Bai, Fei Li, Jiawei Shi, Jianglin Wang, Weihua Qiao*, Nianguo Dong*. Nitric Oxide Generation and Endothelial Progenitor Cells Recruitment for Improving Hemocompatibility and Accelerating Endothelialization of Tissue Engineering Heart Valve. Advanced Functional Materials. 2023, 33(9): 2211267. (Co-corresponding author).
4. Hong Cao^#, Qian Zhou^#, Chungeng Liu, Yecen Zhang, Minghui Xie, Weihua Qiao*, Nianguo Dong*. Substrate stiffness regulates differentiation of induced pluripotent stem cells into heart valve endothelial cells. Acta Biomaterialia. 2022, 143: 115-126. (Co-corresponding author).
5. Xing Chen, Yunlong Wu, Rui Li, Chenghao Li, Li Xu*, Weihua Qiao*, Nianguo Dong*. Galactose-modified nanoparticles for delivery of microRNA to mitigate the progress of abdominal aortic aneurysms via regulating macrophage polarization. Nanomedicine: Nanotechnology, Biology and Medicine. 2022, 44: 102564. (Co-corresponding author).
6. Shuangshuang Zhu^#, Yanting Zhang^#, Weihua Qiao^#, Yixuan Wang, Yuji Xie, Xin Zhang, Chun Wu, Guohua Wan4, Yuman Li, Nianguo Dong*, Mingxing Xie*, Li Zhang*. Incremental value of preoperative right ventricular function in predicting moderate to severe acute kidney injury after heart transplantation. Frontiers in cardiovascular medicine. 2022, 9: 931517. (Co-first author).
7. Xing Chen^#, Wei-hua Qiao^#, Hong Cao^#, Jia-wei Shi, Xin-ling Du*, Nian-guo Dong*. Role of Neuroimmune Interactions in COVID-19-related Cardiovascular Damage. Current Medical Science. 2022, 42(3): 555-560. (Co-first author).
8. Shuyu Wen^#, Ying Zhou^#, Wai Yen Yim, Shijie Wang, Li Xu, Jiawei Shi, Weihua Qiao*, Nianguo Dong*. Mechanisms and Drug Therapies of Bioprosthetic Heart Valve Calcification. Frontiers in Pharmacology. 2022, 13: 909801. (Co-corresponding author).
9. Ge Yan, Yuqi Liu, Minghui Xie, Jiawei Shi, Weihua Qiao*, Nianguo Dong*. Experimental and computational models for tissue-engineered heart valves: a narrative review. Biomaterials Translational. 2021; 2(4): 361–375. (Co-corresponding author).
10. Baocheng Zhang^#, Yuan Xu^#, Sitian Ma, Linfeng Wang, Changjun Liu, Weilin Xu, Jiawei Shi, Weihua Qiao*, Hongjun Yang*. Small-diameter polyurethane vascular graft with high strength and excellent compliance            . Journal of the Mechanical Behavior of Biomedical Materials. 2021, 121: 104614. (Co-corresponding author).
11. Changjun Liu^#, Weihua Qiao^#, Chaorong Wang, Han Wang, Yingshan Zhou, Shaojin Gua, Weilin Xu, Yan Zhuang, Jiawei Shi*, Hongjun Yang*. Effect of poly (lactic acid) porous membrane prepared via phase inversion induced by water droplets on 3T3 cell behavior. International Journal of Biological Macromolecules. 2021, 183: 2205-2214. (Co-first author).
12. Chungeng Liu^#, Weihua Qiao^#, Hong Cao, Jinchi Dai, Fei Li, Jiawei Shi* and Nianguo Dong*. A riboflavin–ultraviolet light A-crosslinked decellularized heart valve for improved biomechanical properties, stability, and biocompatibility. Biomaterials Science. 2020, 8(9): 2549-2563. (Co-first author).
13. Han Wang^#, Weihua Qiao^#, Sitian Ma, Linfeng Wang, Changjun Liu, Yingshan Zhou, Shaojin Gu, Weilin Xu, Jiawei Shi*, Hongjun Yang*. Effect of temperature on the thermal property and crystallization behavior of poly (lactic acid) porous membrane prepared via phase separation induced by water microdroplets. International Journal of Biological Macromolecules. 2020, 147: 1185-1192. (Co-first author).
14. Shuyu Wen^#, Weihua Qiao^#, Yuan Zhang, and Nianguo Dong*. Development and trend in the field of valvular heart disease in China: an analysis based on the National Natural Science Foundation of China. Annals of Translational Medicine, 2020, 8(7): 449. (Co-first author).
15. Jinchi Dai^#, Weihua Qiao^#, Jiawei Shi, Chungen Liu, Xingjian Hu, Nianguo Dong. Modifying Decellularized Aortic Valve Scaffolds with Stromal Cell-derived Factor-1α Loaded Proteolytically Degradable Hydrogel for Recellularization and Remodeling. Acta Biomaterialia, 2019, 88: 280-292. (Co-first author).
16. Wei-hua Qiao^#, Peng Liu, Dan Hu, Mahmoud Al Shirbini, Xian-ming Zhou, Nian-guo Dong*. Sequential hydrophile and lipophile solubilization as an efficient method for decellularization of porcine aortic valve: structure, mechanical property and biocompatibility study. Journal of Tissue Engineering and Regenerative Medicine. 2018, 12(2): e828-e840.
17. Geng Li^#, Weihua Qiao^#, Wenjing Zhang, Fei Li, Jiawei Shi, Nianguo Dong*. The shift of macrophages toward M1 phenotype promotes aortic valvular calcification. Journal of Thoracic and Cardiovascular Surgery. 2017, 153(6): 1318-1327. e1. (Co-first author).
18. Peng Liu^#, Wei-Hua Qiao^#, Fu-Qiang Sun, Xin-Long Ruan, Mahmoud Al Shirbini, Dan Hu, Si Chen, Nian-Guo Dong*. Should a Mechanical or Biological Prosthesis Be Used for a Tricuspid Valve Replacement? A Meta-Analysis. Journal of Cardiac Surgery. 2016, 31(5): 294-302. (Co-first author).
19. Weihua Qiao^#, Nianguo Dong, Peng Liu, Dan Hu, Fayuan Liu, Jiawei Shi. Perfusion decellularization method for the fabrication of decellularized porcine aortic valve scaffold. Chinese Journal of Experimental Surgery. 2016, 33(4): 1023-1025. (Chinese journal)
20. Weihua Qiao^#, Peng Liu, Jiawei Shi, Yin Wang, Nianguo Dong. Changes of Left Ventricular Morphology and Contractile Function after Mitral Valve Replacement of Patients with Mitral Stenosis and Small Left Ventricle: A Meta-analysis. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery. 2016, 23(6): 589-594. (Chinese journal)
21. Weihua Qiao^#, Nianguo Dong, Jiawei Shi. Meta-Analysis of the Association between TBX1 Gene Mutation and Conotruncal Defects. Chinese Journal of Practical Pediatrics. 2014, 29(9): 677-680. (Chinese journal)
22. Weihua Qiao^#, Nianguo Dong. Is there an age limit for the use of biologic valve? Journal of Clinical Cardiology. 2014, 30(9): 745-748. (Chinese journal)
23. Shuyu Wen, Ying Zhou, Weihua Qiao, Yixuan Wang, Jing Zhang, Nianguo Dong. Infant heart transplantation with extremely oversized donor heart: is the donor–recipient size matching too conservative?. ESC Heart Failure. 2023, 10(2): 1431-1434.
24. Yuanming Li, Ying Zhou, Weihua Qiao, Jiawei Shi, Xuefeng Qiu*, Nianguo Dong*. Application of decellularized vascular matrix in small-diameter vascular grafts. Frontiers in Bioengineering and Biotechnology. 2023, 10: 1081233.
25. Yuqi Zheng, Shuyu Wen, Shijiu Jiang, Shaolin He, Weihua Qiao, Yi Liu, Wenling Yang, Jin Zhou, Boyuan Wang, Dazhu Li, Jibin Lin. CircRNA/lncRNA-miRNA-mRNA network and gene landscape in calcific aortic valve disease. BMC genomics. 2023, 24(1): 419.
26. Yuqi Chen, Zongtao Liu, Fayuan Liu, Li Xu, Geng Li, Weihua Qiao, Yixuan Wang, Nianguo Dong. T cell specific deletion of IRF4 with Ox40-Cre impairs effector and memory T cell responses in heart transplantation. Clinical Immunology. 2023, 252: 109647.
27. Xue Chen, Nianguo Dong, Xu Xu, Ying Zhou, Jiawei Shi, Weihua Qiao, Hao Hong. Re-endothelialization of Decellularized Scaffolds With Endothelial Progenitor Cell Capturing Aptamer: A New Strategy for Tissue-Engineered Heart Valve. ASAIO Journal. 2023, 69(9): 885-893.
28. Shuyu Wen, Weihua Qiao, Nianguo Dong. Current status and progress of aortic valve surgery treatment. Journal of Clinical Cardiology. 2023, 39(6): 417-424. (Chinese journal)
29. Peng Bai, Gangcheng Kong, Weihua Qiao, Yu Song, Yixuan Wang, Jiawei Shi, Nan Zhang, Chungeng Liu, Chong Chu, Tixiusi Xiong, Ying Zhou, Cuifen Lu, Lin Wang, Nianguo Dong. A Novel Method to Improve the Physical Property and Biocompatibility of Decellularized Heart Valve Scaffold with Sericin and Polydopamine. Journal of Bionic Engineering. 2022, 19(4): 1109-1123.
30. Chanchan Song, Linli Wang, Qingyang Li, Baoyi Liao, Weihua Qiao, Qiang Li, Nianguo Dong, Liangping Li. Generation of individualized immunocompatible endothelial cells from HLA-I-matched human pluripotent stem cells. Stem cell research & therapy. 2022, 13(1): 1-17.
31. Ming-Hui Xie, Wei-Hua Qiao, Hong Cao, Jia-Wei Shi, Nian-Guo Dong. Progress in the Role of Mechanical Stimulus in Cardiac Development. Acta Academiae Medicinae Sinicae. 2022, 44(1): 164-172. (Chinese journal)
32. Peng Liu, Dong-Sheng Xia, Wei-Hua Qiao, Dan Hu, Adnan Ahmed, Nian-Guo Dong, Si Chen. Which is the best prosthesis in an isolated or combined tricuspid valve replacement?. European Journal of Cardio-Thoracic Surgery. 2021, 59(1): 170-179.
33. Shuangshuang Zhu, Yuji Xie, Weihua Qiao, Fangyan Tian, Wei Sun, Yixuan Wang, Chun Wu, He Li, Luyang Yi, Yi Zhong, Nianguo Dong, Yuman Li, Mingxing Xie, Li Zhang. Impaired left atrial function in clinically well heart transplant patients. The International Journal of Cardiovascular Imaging. 2021, 37: 1937-1945.
34. LinXi Cheng, MingHui Xie, WeiHua Qiao, Yu Song, YanYong Zhang, YingChao Geng, WeiLin Xu, Lin Wang, Zheng Wang, Kai Huang, NianGuo Dong, YuHua Sun. Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells. Communications Biology. 2021, 4(1): 1039.
35. Qin WANG, Yuzhi QIU, Weihua QIAO, Nianguo DONG, Yajiang YANG. Gelation Systems and Mechanisms of Chondroitin Sulfate-Based Injectable Hydrogels. Journal of Functional Polymers. 2021, 34(3): 243-259. (Chinese journal)
36. Shuyu Wen, Weihua Qiao, Nianguo Dong. Applications of enhanced recovery after surgery in cardiovascular surgery. Journal of Clinical Cardiology. 2021, 37(9): 787-790. (Chinese journal)
37. Ge YAN, Wei-hua QIAO, Hong CAO, Jia-wei SHI, Nian-guo DONG. Application of surface modification of polydopamine in tissue engineering. China Biotechnology. 2021, 40(12): 75-81. (Chinese journal)
38. Shuangshuang Zhu, Wei Sun, Weihua Qiao, Meng Li, Yuman Li, Bo Liang, Jing Wang, Nianguo Dong, Li Zhang, Mingxing Xie. Real time three-dimensional echocardiographic quantification of left atrial volume in orthotopic heart transplant recipients: Comparisons with cardiac magnetic resonance imaging. Echocardiography. 2020, 37(8): 1243-1250.
39. Peng Bai, Weihua Qiao, Nan Zhang, Chungen Liu, Jiawei Shi, Nianguo Dong. Advances in research on recellularization of tissue engineered heart valves based on decellularized matrix. Acta Medicinae Universitatis Scientiae et Technologiae Huazhong. 2018, 47(2): 244-250. (Chinese journal)
40. Huadong Li, Jiawei Shi, Weihua Qiao, Nianguo Dong, Gangjian Qin. Abstract 43: SIRT1 Enhances Oxidized Low-density Lipoprotein Induced Autophagy in Human Valve Interstitial Cells. Circulation Research. 2016, 119(suppl_1).
41. Qi Liu^#, Wei-Hua Qiao, Fei-fei Li, Peng Deng, and Zhi-wei Hu*. The Role of Interleukin-13 in Patients with Rheumatic Valvular Fibrosis: A Clinical and Histological Study. Journal of Heart Valve Disease. 2015, 24(4):496-501.

Research Interest:  Designing and preparing new nanobiomaterials Characterizing physical and chemical properties, biocompatibility and bioactivity of the nanobiomaterials

Research Interest: His current research interests include non-linear analysis of biomedical time series, specially the analysis of electroencephalographic and magnetoencephalographic recordings to help physicians in the diagnosis of brain disorders

Research Interest:  His research interests concentrate on the biosensors (e.g. living cell sensor, DNA sensor and protein sensor) and BioMEMS system.

Research Interest: Functional Brain Imaging, Pre-surgical Brain Mapping, Biomedical signal and Image Processing, Neural Engineering

Jin-Won Park received his B.S. degree from Korea University in 1998 and his M.S. and Ph.D. degrees from Purdue University, USA in 2003 and 2005, respectively. From 2007 to 2010, he was an assistant professor at the Gachon University, Korea. Since 2010, he has been a professor at Seoul National University of Science and Technology. His research interests are in biomimetic membranes and their applications.

Research Interests

Biophysics of Interfaces

The cell membrane, the interface between the cell and its environment, is the functional element in cellular metabolism and signaling. A great deal is found about the lipid, protein and saccharide constituents of membranes and their organization, and the physical properties are related with structures and functions.

A model has been utilized to study the physical properties of the cell membranes in which (glyco) proteins such as integrins, selectins, and lectins are involved in cellular interactions. On the other hand, direct measurements of the surface forces between lipid bilayers of phosphatidylethanolamine, phosphatidylcholoine, and galactolipids, the most common lipids in animal and plant membranes, suggest strong repulsive forces between highly hydrated head groups, which prevent membranes from coming into contact and reacting, adhering or fusing. Much could be known about the function and organization of the membrane's constituents if the physical properties of membranes could be measured with nano-meter scale lateral resolution.

Biosensing Platforms

Early detection of infectious diseases is important to enhance the quality of medical care and limit the spread of emerging infectious diseases. Thus, there is a need for rapid, sensitive, and inexpensive point-of-care sensors that have capability to identify multiple pathogens in complex samples such as blood.

Novel techniques have been developed for sensing pathogens, based on microfluidics. Eventually, the techniques will be platform for high throughput with low sample volume reagents and highly selective analyte sensing. These assays are designed to abstract molecular level details and mechanistic insights from biophysical and bioanalytical problems that would otherwise be difficult to approach.

Research Interest: Bone and cartilage disease modeling, drug screening and gene correctionDirect differentiation of pluripotent stem cells toward cartilage and boneBone reprogramming of fibroblasts using defined factors Gene therapy for cartilage regeneration and repair in regenerative medicine Signaling pathway of genes regulating cartilage differentiation of human mesenchymal stem cells.Molecular basis of mesenchymal stem cells maintaining their stemness. Stem cell biology and technique

Publications List:

1. Liu TM*, Yingnan Wu. Editorial: Advancing Gene and Cell Therapy using Human Mesenchymal Stem Cells. Front Cell Dev Biol, 2023, 11:1294460. doi: 10.3389/fcell.2023.1294460. eCollection 2023. (IF 6.081, *corresponding author). Published on 13 Oct 2023.
2. Yufeng Shou, Ling Liu, Zhicheng Le, Khang Leng Lee, Xianlei Li, DionZhanyun Koh, Yuwen Wang, Tong Ming Liu, Zheng Yang, Chwee Teck Lim, Christine Cheung, Andy Tay. Mechano-responsive hydrogel for directing stem cell manufacturing and therapy. Bioact Mater, 2023, 24:387-400. doi: 10.1016/j.bioactmat.2022.12.019. eCollection 2023 Jun. eCollection 2023 Jun. (IF 16.44). (2023 Jan 2)
3. Liu TM*. Application of mesenchymal stem cells derived from human pluripotent stem cells in regenerative medicine. World J Stem cells, 2021,13(12): 1826-1844. doi: 10.4252/wjsc.v13.i12.1826  (Invited review, IF 5.326, *corresponding author). (2021 Dec 26)
4. Srinivasan A, Sathiyanathan P, Yin L, Liu TM, Lam A, Ravikumar M, Smith RAA, Loh HP, Zhang Y, Ling L, Ng SK, Yang YS, Lezhava A, Hui J, Oh S, Cool SM. Strategies to Enhance Immunomodulatory Properties and Reduce Heterogeneity in Mesenchymal Stromal Cells during ex vivo Expansion. Cytotherapy (IF 5.414). 2022 May;24(5):456-472. doi: 10.1016/j.jcyt.2021.11.009. Epub 2022 Feb 25. PMID: 35227601
5. Liu TM*, Yildirim ED, Li P, Fang HT, Denslin V, Kumar V, Loh YH, Lee EH, Cool SM, Teh BT, Hui JH, Lim B, Shyh-Chang N. Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells.  Stem Cell Reports, 2020, 14:210-225 (IF 7.765, *corresponding author, cited 7). doi: 10.1016/j.stemcr.2020.01.002. Epub 2020 Jan 30. 11 February 2020.
6. Liu TM*. Regulation of chondrogenesis. Ann Stem Cell Res Ther. 2019; 3(1): 1028. (Invited Editorial, *corresponding author).
7. Liu TM, Shyh-Chang N. SIRT2 and glycolytic enzyme acetylation in pluripotent stem cells. Nat Cell Biol. 2017 Apr 27; 19(5):412-414. doi: 10.1038/ncb3522 (IF 20.06, cited 12).
8. Liu TM*. Stemness of Mesenchymal Stem Cells. J Stem Cell Ther Transplant. 2017; 1: 071-073 (Invited Editorial, *corresponding author, cited 9).
9. Cheng H, Ang HY, A El Farran C, Li P, Fang HT, Liu TM, Kong SL, Chin ML, Ling WY, Lim EK, Li H, Huber T, Loh KM, Loh YH, Lim B. Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors. Nat. Commun. 2016 Nov 21; 7:13396. doi: 10.1038/ncomms13396 (IF 11.3, cited 17).
10. Liu TM*, Lee EH, Lim B, Shyh-Chang N. Balancing Stem Cell Self-renewal and Differentiation with PLZF. Stem cells, 2016 Feb; 34(2):277-87. doi: 10.1002/stem.2270. Epub 2016 Jan 5 (IF 7.133, *corresponding author, cited 54).
11. Liu TM*. Stem Cell-Based Therapies for Cartilage Repair and Regeneration. J Stem Cells Res, Rev &. Rep. 2014, 1(1): 1-2 (Invited Editorial, *corresponding author).
12. Tan HK, Toh CX, Ma D, Yang B, Liu TM, Lu J, Wong CW, Tan TK, Li H, Syn C, Tan EL, Lim B, Lim YP, Cook SA, Loh YH. Human Finger-Prick Induced Pluripotent Stem Cells Facilitate the Development of Stem Cell Banking. Stem Cells Transl Med. 2014 May; 3(5):586-98. doi: 10.5966/sctm.2013-0195. Epub 2014 Mar 19. (IF 5.709, cited 42)
13. Liu TM*, Lee EH. Transcriptional regulatory cascades in Runx2-dependent bone development. Tissue Eng Part B Rev, 2013, 19(3):254-63. doi: 10.1089/ten.TEB.2012.0527. (*corresponding author). (IF 4.448, cited 238)
14. Liu TM*, Ng WM, Tan HS, Vinitha D, Yang Z, Fan JB, Zou Y, Hui JH, Lee EH, Lim B. Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression. Stem Cells Dev. 2013 Jan 15; 22(2):268-78. doi: 10.1089/scd.2012.0222. Epub 2012 Aug 21. (IF4.67, *corresponding author, cited 67).
15. Liu TM*. Gene therapy for articular cartilage repair. Pharmaceutica Analytica Acta, 2012,3:e1112. doi:10.4172/2153-2435.1000e112 (Invited Editorial, *Corresponding author).
16. Yang Z, Zou Y, Guo XM, Tan HS, Denslin V, Yeow CH, Ren XF, Liu TM, Hui JH, Lee EH. Temporal activation of ß-catenin signaling in the chondrogenic process of mesenchymal stem cells affects the phenotype of the cartilage generated. Stem Cells Dev. 2012, 21:1966-1976. 2011 Dec 1. [Epub ahead of print]. (IF4.791, cited 35).
17. Liu TM^*, Guo XM, Tan HS, Hui JH, Lim B, Lee EH. Zinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repair. Arthritis Rheum. 2011 Sep; 63(9):2711-20. doi: 10.1002/art.30430. (IF8.435, *Corresponding author, cited 72).
18. Liu T, Liu L, Wei Q, Hong Y. Sperm nuclear transfer and transgenic production in the fish medaka. Int J Biol Sci, 2011, 7(4): 469-475. (IF 3.215, cited 22)
19. Liu TM, Wu YN, Guo XM, Hui JH, Lee EH, Lim B. Effects of ectopic Nanog and Oct4 overexpression on mesenchymal stem cells. Stem Cells Dev. 2009 Sep;18(7):1013-22. doi: 10.1089/scd.2008.0335. (IF4.45, cited 164)
20. Liu TM, Martina M, Hutmacher DW, Hui JH, Lee EH, Lim B. Identification of common pathways mediating differentiation of bone marrow- and adipose tissue-derived human mesenchymal stem cells into three mesenchymal lineages. Stem Cells. 2007 Mar;25(3):750-60. doi: 10.1634/stemcells.2006-0394. Epub 2006 Nov 9. (IF 7.751, cited 524)
21. Lian Q, Lye E, Suan Yeo K, Khia Way Tan E, Salto-Tellez M, Liu TM, Palanisamy N, El Oakley RM, Lee EH, Lim B, Lim SK. Derivation of clinically compliant MSCs from CD105+, CD24- differentiated human ESCs. Stem Cells. 2007 Feb; 25(2):425-36. doi: 10.1634/stemcells.2006-0420. Epub 2006 Oct 19. (IF 7.751, cited 298).
22. Y.H. Hong, T.M. Liu, H.B. Zhao, H.Y. Xu, W.J. Wang, R. Liu, T.S. Chen. Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro. Proc. Natl. Acad. Sci. USA., 2004, 101(21): 8011-8016. (IF 10.3, cited 213)
23. Y.H. Hong, C. Winkler, T.M. Liu, G.X. Chai, M. Schartl. Activation of the mouse Oct4 promoter in medaka embryonic stem cells and its use for ablation of spontaneous differentiation. Mech. Dev., 2004, 121: 933-943. (IF 3.16, cited 61)
24. TM Liu, QJ Wu, YZ Ye. Studies on the artificial induce gynogenesia and the sex revesal in loach (Misgurnus anguillicaudatus). Acta Hydrobiologica Sinica, 2004, 28: 445-447 (cited 6).
25. TM Liu, XM Yu, YZ Ye, JF Zhou, ZW Wang, JG Tong, QJ Wu. 2002. Factors affecting the efficiency of somatic cell nuclear transplantation in the fish embryo. The Journal of Experimental Zoology, 2002, 293:719-725 (cited 20)
26. T. M. Liu, Q. J. Wu, X. M. Yu, X.Y. Li. Effects of cell-cycle arrest agents on cleavage and development of loach (Misgurnus anguillicaudatus) embryos. Fish Physiology and Biochemistry, 2002, 25:3-9.
27. TM Liu, XM Yu, YZ Ye, ZW Wang, JF Zhou, QJ Wu. Studies on factors affecting the development of embryos from somatic cell nuclear transplantation in the fish. Zoological Research, 2002, 23(2): 107-112.
28. YD Liu, LR Song, XY Li, TM Liu. The toxic effects of microcystin-LR on embry-larval and juvenile development of loach, Misgurnus Mizolipis Gunthe. Toxicon, 2002, 40(4): 395-399 (cited 137).
29. TM Liu and QJ Wu. 2000. Progress of nuclear transplantation in teleost.   Biotechnology Information, 6:24-28.
30. TM Liu, JW Cao, LY Wan, Y Liu, YX Yu. Subcloning of alkalophilic gene from alkalophilic Bacillus sp. NTT36 and its expression in Escherichia coli and Agrobacterium tumefaciens. Amino Acids & Biotic Resources, 1999, 21(2): 37-40.
31. LY Wang, JW Cao, TM Liu, XQ Zhang. Cloning and expression of promoter from an alkalophilic Bacillus sp. NTT89 in Escherichia coli. Journal of Wuhan University (Natural Science Edition), 2000, 46(2): 257-260.
32. Y Gong, JW Cao, TM Liu. Clone and subclone of the alkalophilic gene from alkalophilic Bacillus sp. NTT36 and analysis of expressed products in E.coli. Journal of Wuhan University (Natural Science Edition), 1998, 44(6): 775-780.

Research Interest: Nano-Biomaterials Development, Cellular and Tissue Engineering Drug and Gene Delivery, Molecular Diagnostics Photobioreactor Design

Research Interest: Military toxicology; Acetylcholinesterase reactivators as treatment of nerve agent and pesticide intoxications; Acetylcholinesterase inhibitors in Alzheimer´s disease and Myasthenia Gravis treatment; Synthesis of the detergents as disinfectants, decontamination means and environment for micellar catalysis; Drug design and Development; Chemical warfare agents; Biological warfare agents; Pharmaceutical Industry; Project Management; Scientific Management; Technology Transfer; Commercialization; Fund Raising; Cloud computing; Parallel computing; medical devices development; toxins. 

Research Interest: Connective Tissue, Drugs Action, Microscopy, Protein Modeling, Bone Structure, Trace/major Elements, Image Processing, Electromagnetism, Spectroscopy, Biometrics, Human Networks

Research Interest: Image / signal processing, Machine learning, Computer-aided clinical diagnosis and treatment selection